What is LSD and is it Addictive? A synthetic crystalline substance, lysergic acid diethylamide, which is a powerful hallucinogenic drug. LSD is among the most mood-changing, potent chemicals. It is produced from lysergic acid, which is found in the ergot disease that grows on rye and other grains. It's produced in crystal form in illicit laboratories, mostly in the United States. These crystals are converted to a liquid for distribution. It's colorless, odorless, and has… "What is L.S.D"